But the most significant all...

The report makes a significant attempt to address an important issue.

Development is a global issue of critical dimensions and significant implications.

Significant progress on this issue has been achieved since my last report.

This is a significant issue already covered in part in the Convention.

It is not only a moral issue health inequalities carry significant economic costs.

Meanwhile, ordinary citizens do not notice unless the issue receives significant media attention.

Those proposals, which address the heart of the issue, constitute a significant development.

There remains the most fundamental issue of attitude.

The independent expert did not observe any significant progress on the issue of impunity.

While the international community has given the issue significant attention, it is not enough.

I believe that perhaps the most significant issue we are considering at the summit is cooperation to reduce the gaps between the various development levels of the world's nations.

Consider China, by many measures the most significant emerging country.

Like most committee chairs, they have significant agenda setting power.

Dublin was the most significant settlement in the long term.

Longlines are the most significant threat to these species' survival.

The issue of safety should be considered most seriously.

Awareness can be the most significant factor in motivating environmental action.

The result that has been achieved is for us most significant.

It's probably the most significant, evolutionary step forward since walking upright.

I heard it was the station's most significant tragic love drama.

They understand this is the most significant intervention they can make.

The issue most prominent in the submissions related to documentation.

This issue is the most important item on our agenda.

What's the most important issue to you this election season?

(What's the most important issue to you this election season?)

What's the most important issue to you this election season?

But the most significant issue coming to the fore in hemispheric relations is immigration. Traditionally a Mexican, Central American, and Caribbean matter, it has now reached Brazil, Colombia, Venezuela, Ecuador, and beyond.

It was one of the most significant laws of pre war Japan.

Among these, one of the most significant was 230(o), which stated

The most significant aspects of the Money Laundering Act are as follows

Most areas of the Secretariat are undergoing significant changes in this respect.

It's almost like their radar is attuned to the most significant moments.

This is the most delicate issue of all for South Korea.

What is the most important issue to you this election season?

And many scientists believe it's the most serious issue facing mankind.

What is the most important issue to you this elections season?

What is the most important issue for you this election season?

The government's land distribution is perhaps the most crucial and most bitterly contested political issue surrounding Zimbabwe.

When respondents are asked what the most important problem facing the country is, they answer with the most accessible news issue in memory, which is typically the issue the news media focused on the most.

Most important, significant gains in health could be attained with adequate financial resources.

The most significant problem would be capital losses for core eurozone financial institutions.

This is, by far, one of the most significant I have ever seen.

Satellite imagery of the most significant sites continues to be collected and assessed.

Among the most significant aspects of the law, the following merit special mention