The global security architecture is undergoing profound change.

I understood that there was a profound change occurring in Nathaniel's eyes.

This is a profound change that creates much friction in the transitional phase.

And I've had to mark the hill because the change is so profound.

Disruptive change may be required, and here each of us can make a profound difference.

The international community bears a solemn responsibility to assist in bringing about this profound change.

I think that this is a really profound change in the way human affairs are arranged.

Research tells us that it takes up to 15 of committed consumers to trigger a profound change.

Their slogans describe their rage and anger. Their demands are a reflection of a profound desire for change.

Following the Programme's adoption, the bodies responsible for formulating and implementing Mexico's youth policies underwent a profound change.

The Conference provoked a profound change in the population debate by placing priority on issues of human rights.

Given Europeans complicated experience with European Union enlargement, they should understand the challenges that accompany such a profound change.

Climate change poses a profound threat to our economic future, while low carbon growth promises decades of increased prosperity.

But there is no denying that technological change nowadays has accelerated, potentially leading to deeper and more profound dislocations.

Its priority has been to ensure that the profound political and economic change does not result in global conflict.

The change was intended to reflect the profound transformations now under way in Africa as leaders begin to implement NEPAD.

Very profound.

Indeed, without profound structural change, the favorable standard of living that underpins the Gulf states political stability is likely to erode.

And that is going to change our worldview in a profound way not in a dissimilar way as 400 years ago,

Extremely profound experience.

Profound leaps forward!

And much of the additional spending needs be made by households, driven by a profound change in social attitudes to energy efficiency.

It was concluded that the actions outlined required a profound change in the character of the Department and in its operations (para.

There is still one case about which we are concerned and about which we have repeatedly expressed our hope for profound change.

Thus, the interim accord is a truly remarkable and forward looking achievement which promises to bring fundamental and profound change to South Africa.

The consequences are profound.

Tesla's insight was profound.

That's the profound switch.

Deep, Marion. Profound, Marion.

While the world s educational needs are huge, and the importance of meeting them is profound, the international community s capacity to deliver change is growing.

As a neighbouring country, Romania has joined with particular enthusiasm in the international support for the profound process of democratic change in the area.

Further details about the consequences of this profound change in global atmospheric composition and about scientific progress and obstacles in addressing such issues are covered in the section on climate change (see sect. III above).

If SETI does nothing but change the perspective of humans on this planet, then it will be one of the most profound endeavors in history.

America needs profound soul searching.

Therein lies a profound contradiction.

This is a profound error.

They had profound intellectual disabilities.

It's an extremely profound experience.

It's simple, but incredibly profound.

These are profound linear changes.

And this is extremely profound.

Beethoven's music is very profound.

I was caught off guard when Stephen Colbert asked me a profound question, a profound question.

I was caught off guard when Stephen Colbert asked me a profound question, a profound question.

But one might conclude from the bizarre debates we engage in about climate change that what the world needs is a change in its political and psychological mood, rather than a profound social and economic transformation.