Nonetheless, the United Nations now operates in a radically different world from that of 1945, and the Charter should reflect the realities of today.

This situation changed dramatically during the 20th century.

Humans have fundamentally altered Earth s ecosystems.

Furthermore, the problem is linked to the illegal trade in small arms and light weapons.

As we mark the sixtieth anniversary of the founding of the United Nations, we are not only reaffirming the vision and the hope of 1945, but we are also hoping to reform the Organization's organs and its working methods so as to make it better able to serve us in today's world, which is radically different from that of 1945.

Since that time, the population and health situation in the world has changed dramatically.

The economic, social and environmental conditions of the Maldive islands changed fundamentally within a matter of hours.

It is here that economists disagree.

If Syria changed sides, the situation in the region would be fundamentally transformed.

The euro crisis has now turned the EU into something radically different.

After his first chemotherapy session, Chávez exclaimed I am radically changing my life.

This time is no different.

This year was no different.

The pulse varies with age.

The euro crisis, however, has turned the EU into something radically different.

First, European leaders agreed in June 2012 on a major overhaul of the eurozone.

It's no different than checking an email.

Farmers are a different story.

Things won t be much different in Portugal.

It s the same globally.

Of course, these two approaches are not fundamentally incompatible and a good economy needs both.

It's no different than sending a text.

My wife's taste in dress is contrary to my own.

But China s current situation is vastly different.

But the case of Germany is different.

How different it is in Western Europe.

The origin of the signal varies, depending on the continuity and medium.

The situation is similar in trade in services.

It undercuts self righteousness, radically alters the tone and character of controversy, and enriches dramatically the possibilities for finding common ground.

By revolution, I mean a drastic and far reaching change in the way we think and behave the way we think and the way we behave.

But government dishonesty is not that different.

But Mockus is different.

Tariq Al Kindari adds

I suppose it's different when you think about it over the long term.

It differs in significant ways from the work of Sophocles.

At the heart of the description are ideas of quantum state and quantum observable which are radically different from those used in previous models of physical reality.

This shows that pre natal care, especially intensive care for newly born babies, has improved drastically.

The announced withdrawal of the Democratic People's Republic of Korea from the Treaty on the Non Proliferation of Nuclear Weapons poses a fundamental challenge to the Treaty.

The two men differ in temperament as well as experience.

Terrorism today, however, is different from what it was in the past.

It is one thing to support a people that is being oppressed by an authoritarian government.

The ECB is different, for some good reasons.

But the evolution of the Greek crisis is different from the Asian crisis.

The necessary balance may vary according to local conditions.

The third quarter is shaping up to be much like the second.