The challenges facing Kim are piling up.

These heme like substances theoretically inhibit ALA synthase and hence the accumulation of toxic precursors.

This pressure for change has been building for years.

They accumulate in the tissue of living organisms, which absorb POPs through food, water, and air.

(e) Annual leave shall accrue during the period of maternity leave.

These are times when central banks need to spend some of the credibility that they accumulate in normal times.

Even functional mitochondrial genes accumulate mutations faster and more freely.

But most high productivity services require a wide array of skills and institutional capabilities that developing economies accumulate only gradually.

As evidence mounts that the attacks were planned and directed from Pakistani territory, calls for decisive action have intensified.

Pesticides and other toxic substances bioaccumulate i.e., creatures higher up the food chain will store more of them in their body fat.

People are feeling overwhelmed. They're feeling like it's too much technology too fast.

They are built by ejecta from a volcanic vent, piling up around the vent in the shape of a cone with a central crater.

At the same time, aquifers tapped for domestic use increasingly have unsafe levels of naturally occurring contaminants, including arsenic and fluoride.

But if external demand lags, products accumulate, prices decline, and profits fall.

We know from measurements that greenhouse gases are accumulating in Earth s atmosphere.

That is why countries build up debt levels that put them in the danger zone.

Obviously, debt accumulates wherever people want to spend more than they have saved.

Every day, new Palestinian sorrows strike heaven in the face.

Most of it is because of ways that the liabilities are building up and the trends, and that creates a huge challenge.

The twentieth century left heaps of corpses in its wake, and now they are piling up again.

Prior to the crisis, American consumers, on average, either saved nothing or accumulated debt.

Who wants to build up debt if there might be a financial crisis around the corner?

Even small errors in the original data can accumulate into substantial error later in the simulation.

Symptoms accumulate over several months and include fever, cough, breathlessness, wheezing, and weight loss.

But protectionist pressures are building as weary politicians hear more and more calls for economic nationalism.

It may pile up in bank reserves or savings accounts, or it may produce asset bubbles.

When they made money, it accrued principally to the family itself.

Such white mineral deposits accumulate to a surface thickness of several millimeters and must be removed by chemical or mechanical means.

Delay is as dangerous as the gathering greenhouse gas concentrations.

Today, pressure is increasing for the US Treasury to follow Nixon s misguided example and issue a finding (due by April 15th) that China is manipulating its exchange rate.

Countries like the US and the UK, which are accumulating debt at a record pace, are betting that deficit spending will eventually pay off in a stronger economy.

China s ascent, however, is dividing Asia, and its future trajectory will depend on how its neighbors and other players, like the US, manage its rapidly accumulating power.

After they accumulate large amounts of cytoplasmic membranes (with associated high cholesterol content) they are called foam cells.

Homework is another thing. There are homework bans springing up all over the developed world in schools which had been piling on the homework for years, and now they're discovering that less can be more.

Europe needs a sense of purpose for a century in which many of the odds will be stacked against it, as well as a statement of the moral standards that will guide its actions and, one hopes, its leadership.

Nonetheless, nominal rates do matter. When they are negligible, they flatter profit statements, while balance sheet problems slowly accumulate.

I gave when I was cornered, when it was difficult to avoid and I gave, in general, when the negative emotions built up enough that I gave to relieve my own suffering, not someone else's.

Given that most of these items are not biodegradable, and are not recycled, plastics waste is building up with serious environmental consequences.

This is true both for the public infrastructure (drains, depressions where water accumulates during the rainy season, broken drinking water supply pipes) and in the private homes (roof top, drinking water tanks, and water collections inside and around the house).

Europeans may want a more normal America, closer to their own values, but they simultaneously worry that a more modest America would demand more of them in the realm of hard military power.

In the integumentary system, which includes the skin, it accumulates in the deepest level, the subcutaneous layer, providing insulation from heat and cold.

But the difference is that these cultures never expand, never grow, never accumulate, never become combinatorial, and the reason is because there is no sex, as it were, there is no exchange of ideas.

The middle line is millions of tons of plastic debris accumulating in our ocean, and the third line is radioactive material leaking from Fukushima nuclear power plant in the Pacific Ocean.

When you sell more to the world than you buy, you accumulate claims on the rest of the world and you need to decide the form in which you want to hold those claims.

Although bilateral tensions began to build from 1998 onward, due to the Taliban s refusal to turn over Osama bin Laden to Saudi Arabia (his homeland), the Kingdom still hoped that petro dollar diplomacy might solve this problem.