The signs of this shift are profound, even spectacular.

Friedman was the catalyst for a profound shift in how governments conduct economic policy.

France s profound political shift reflects the persistence of the economic crisis that began in 2008.

This shift will have profound implications for China, the rest of Asia, and the broader global economy.

The world is on the cusp of the most profound shift in global power and influence in a century.

Not so long ago, however, this saying was understood quite differently, indicating a profound shift in the way that we think about our diet and ourselves a shift that has powerful implications for current health debates.

The fact that relatively moderate shocks have caused such profound trauma in emerging markets makes one wonder what problems a more dramatic shift would trigger.

It is likely that growing natural resource scarcities are driving a paradigm shift, with potentially profound implications for economies and thus for sovereign debt risk worldwide.

In their wake, a notable shift has emerged, with a new generation of politicians claiming to herald a fresh approach and profound changes in French policy towards Africa.

The other 30 is also emblematic of a deeper strategic issue that America faces a profound competitive challenge. A shift to external demand is not there for the asking.

Extremely profound experience.

The very name the first machine age was the Industrial Revolution suggests an epochal shift. And, indeed, if the predictions are to be believed, these technological advances could have profound implications for the way we live.

CAMBRIDGE OXFORD The Obama administration s so called pivot to Asia is the most important strategic shift that the United States has undertaken since the end of the Cold War and it has profound implications for Europe.

The consequences are profound.

I was caught off guard when Stephen Colbert asked me a profound question, a profound question.

The shift system operates in a morning shift from 8.45 to about 13.00, and an afternoon shift until about 18.30.

The shift system operates in a morning shift from 8.45 to about 13.00, and an afternoon shift until about 18.30.

America needs profound soul searching.

Therein lies a profound contradiction.

This is a profound error.

Tunisia, too, is facing profound polarization.

(right shift) .REM.

The US has made profound missteps recently.

Reform has stalled amid profound political paralysis.

That shift is understandable.

Clearly, humans who now occupy almost 40 of the planet s ice free land surface are shaping many of the planet s fundamental processes. According to Nobel laureate Paul Crutzen, this shift is so profound that it amounts to the beginning of a new epoch the Anthropocene.

Swami Dayananda Saraswati The profound journey of compassion

Europe suffers from a profound crisis of confidence.

The implications of this linguistic variety are profound.

Destination countries have equally profound responsibilities in crises.

The disruption, particularly to credit, would be profound.

Selecting our children raises more profound ethical problems.

Profound wisdom but warnings are of no avail .

Profound wisdom but warnings are of no avail .

This sixtieth anniversary year is of profound significance.

The global security architecture is undergoing profound change.

In the European Union, on the other hand, since the shift occurs at 01 00 UTC, the autumn shift happens an hour later than the spring shift, local time.

My shift ends at five.

China s shift has been dramatic.

In a profound way, they are all deeply conservative.

The implication of this position is profound and shocking.

Indeed, relations with China are Japan's most profound problem.

A look beyond the cordial rhetoric reveals profound differences.

The policy implications of such a reorientation are profound.

Finally, there is a profound moral issue at stake.