This sixtieth anniversary year is of profound significance.

But the European Central Bank, notably by ECB board member Lorenzo Bini Smaghi, has elegantly spelled out the case against debt reduction a case that is politically significant and deeply moral.

It makes good political sense it could make good business sense as well.

Historical traditions also play a role.

At a single stroke, Buffett has given purpose to his life.

Ukraine considers reform of the Security Council to be of exceptional international significance.

Its agenda and mandate must be meaningful. Its administration must be reformed.

I was caught off guard when Stephen Colbert asked me a profound question, a profound question.

Philip Rosedale I think that's great. That's such a deep question. Yeah.

I'm going to take you on a deep dive.

Sami fell into a deep depression.

It is deeply appreciated.

There is a need for substantive engagement, so that a leaders meeting makes sense.

For African Americans, Ghana has special meaning.

We hope that such a dialogue will be a meaningful one this time.

The greatness of that event carries with it a truly fateful significance for all of humankind.

It was a deeply confused speech.

Therein lies a profound contradiction.

Those developments are deeply disturbing.

We need deep, systemic change.

Another deep cave in the valley, located in its very upper part and explored by Moldavian and Ukrainian cavers is Berchilskaya Cave, deep.

Cameron s remarks were deeply resented in Pakistan.

The problem is that it remains a departure without any meaningful destination.

A decade later, that proposal still seems meaningful.

The year 2005 is a significant one for Kosovo and the whole region of the Western Balkans. We need stability and security in Kosovo.

So there is a spirit of equality, combined with deep inequalities.

Reform has stalled amid profound political paralysis.

There is a deep logic to this finding.

Merkel has changed profoundly while in office.

But now, I get ashamed every time I recall how we used to call her.

Azerbaijan, Turkmenistan, and Uzbekistan regularly boycott the CIS s meaningless annual summits.

For years, China has also blocked meaningful sanctions against Burma.

So no possibility of medical response to, or meaningful preparedness for all out nuclear war.

Unlike the token gestures of reform offered by previous rulers, Sein s actions appeared substantive and meaningful.

Most presidents hope to attach some special meaning to their time in office.

Cardinal Wojtyla s election as Pope therefore had a significance far beyond the confines of the Church.

Our road map to peace includes an inclusive process to make democracy meaningful and to provide good governance for the people.

This now needs to move beyond slogans to meaningful action on the ground.

These rights are meaningless without sufficient land over which to exercise them.

Efforts to prevent conflicts were meaningless if the economic roots of those conflicts were not addressed.

The winners and losers are clear, and the political landscape has changed profoundly.

But, as of early December, Britain has remained dormant.

They plot injustice, saying, We have made a perfect plan! Surely man's mind and heart are cunning.

They search out iniquities they accomplish a diligent search both the inward thought of every one of them, and the heart, is deep.

The administration of justice continues to be an issue of deep concern.