Most presidents hope to attach some special meaning to their time in office.

This is an especially significant year, as it marks the sixtieth anniversary of the establishment of the United Nations.

It makes good political sense it could make good business sense as well.

Historical traditions also play a role.

According to this view, the altered state of consciousness produced by ketamine particularly the dissolution of the self s boundaries and the experience of union with the world might constitute a profound and meaningful experience for a patient.

At a single stroke, Buffett has given purpose to his life.

Ukraine considers reform of the Security Council to be of exceptional international significance.

Its agenda and mandate must be meaningful. Its administration must be reformed.

There is a need for substantive engagement, so that a leaders meeting makes sense.

For African Americans, Ghana has special meaning.

We hope that such a dialogue will be a meaningful one this time.

The greatness of that event carries with it a truly fateful significance for all of humankind.

This sixtieth anniversary year is of profound significance.

The problem is that it remains a departure without any meaningful destination.

A decade later, that proposal still seems meaningful.

The year 2005 is a significant one for Kosovo and the whole region of the Western Balkans. We need stability and security in Kosovo.

Fifth, and finally, draft resolution A 59 L.68 provides for meaningful and effective Security Council reform, but without forcing divisive and potentially damaging votes on the General Assembly as individual States vie among themselves for special status.

Azerbaijan, Turkmenistan, and Uzbekistan regularly boycott the CIS s meaningless annual summits.

For years, China has also blocked meaningful sanctions against Burma.

So no possibility of medical response to, or meaningful preparedness for all out nuclear war.

Unlike the token gestures of reform offered by previous rulers, Sein s actions appeared substantive and meaningful.

Cardinal Wojtyla s election as Pope therefore had a significance far beyond the confines of the Church.

Our road map to peace includes an inclusive process to make democracy meaningful and to provide good governance for the people.

This now needs to move beyond slogans to meaningful action on the ground.

These rights are meaningless without sufficient land over which to exercise them.

Efforts to prevent conflicts were meaningless if the economic roots of those conflicts were not addressed.

Kuti thought that art, and thus his own music, should have political meaning.

If a State made such a declaration, its accession to the convention would be virtually meaningless.

And marble cake is significant because it is the channel that this group called Anonymous organized.

Liberia s progress has significance well beyond its immediate borders and those of its neighbors in West Africa.

At first, it's very unintuitive, but when you actually think about it from their point of view, it makes a ton of sense.

One would think that market prices should be volatile as investors try to absorb what this earnings volatility means.

Because the 90 threshold had become political fodder, its subsequent demolition also gained broader political meaning.

The situation is scarcely improved by including a provision that foresees an illusionary and meaningless review in the very distant future.

Council reform will make sense only if its purpose is to better reflect today's geopolitical realities.

Asser Press, 2002, The Hague, Netherlands.

An initial assessment of the offers reaffirmed that those tabled in their current form had not put forward meaningful improvements.

So there was a lot of meaning in my life because I was performing this type of research during the day.

It provides a sense of purpose and mastery two key motivational things that increase productivity, through play.

Nevertheless, the fact that it has been taken up by the world s most famous business school is significant.

Finally, CAFTA fails to address labor issues in any significant way.

The delay is significant, because Kuwaitis are unaccustomed to this kind of parliamentary influence.

We therefore feel that for any United Nations reforms to be meaningful, we need assistance in the areas of good governance.

Which leads me to think that neither geography nor national character, popular explanations for this kind of thing, are really significant.

The choice was between a minor story critical of Taiwan and a larger piece about a domestic issue of potentially historic significance.