This is one area that requires a major institutional shift, otherwise the issues might become unmanageable.

Mobile phones made a bigger difference to the lives of more people, more quickly, than any previous technology.

It's been a roller coaster ride.

But this was transformative. Really transformative.

You could see the turnaround in Assad almost immediately.

So we're seeing a great change in terms of diffusion of power.

And this article from The Economist summed it up beautifully about the opportunities in health across the developing world Mobile phones made a bigger difference to the lives of more people, more quickly, than any previous technology.

Notes that UNOPS client base has shifted substantially to meet changing demands for services in post conflict and natural disaster response environments, and infrastructure and complex operations management with capacity building support

By educating girls, we will trigger a transformation of society as a whole social, economic and political.

So, as you can imagine, this was a paradigm shift in the survey and construction as well as in reality capture industry.

Placing the Millennium Development Goals at the centre of national strategies requires a fundamental shift in approach.

We also said that the 21st century would see shifting climate zones, creation of drought prone regions in North America and Asia, erosion of ice sheets, rising sea levels and opening of the fabled Northwest Passage.

I think actually this is not so much a shift from the West to the East something different is happening.

And this inspired in my mind a shift from transplanting whole organs to perhaps transplanting cells.

Not much breaking though. No, not much.

I too was fascinated by this new and disruptive cell technology, and this inspired a shift in my mindset, from transplanting whole organs to transplanting cells.

But we also say that countries like ours, which is undergoing a profound transition, should not be held to unrealistic standards.

The volume reduction in operating expenses reflects a shift to increased proportionality between regular and other resources.

The reflection would be around the second coordinate's axis. It seems like it would be a more natural transformation.

When we really cite these great moments in art he was able to do something that was a huge transition and influential of things that came after him.

But this conclusion would ignore a tectonic shift taking place in Egypt far from the cameras in Tahrir Square.

It means I set a price on myself, a high, high price.

It takes a big army for that. We'll have a big army.

Isn't he grand?

So, as you can imagine, this was a paradigm shift in the survey and construction as well as in reality capture industry.

The World Programme represented a significant move away from the traditional approach that focused on rehabilitation measures aimed at disabled individuals.

Net portfolio flows displayed in the table have also been volatile and, since 2000, appear to have turned significantly negative.

This unprecedented achievement is transforming all sectors and institutions of societies worldwide.

(3) We would be much better off if X were done away with, or at least radically transformed.

New cash transfer procedures are being introduced which are a major, simplifying change for UNICEF and its partners.

Its role was significant.

They broke new ground.

That made all the difference.

He was a big kid.

Make it a large one.

Big things ? Ha.

It is revolutionary in that the Department has undergone a transformation from conference services to conference management and is gradually moving towards integrated global management.

Promoting peace and security in the twenty first century requires a fundamental shift in how we respond to the challenge of violent conflict.

Well it seems to me that we're now seeing a fundamental shift of power, broadly speaking, away from nations gathered around the Atlantic seaboard to the nations gathered around the Pacific rim.

That represents great progress.

We have made remarkable progress.

They don't have a lot of volume.

This was a big thing that

You made a huge decision.

It makes a big difference.