There is despondency and latent unrest. Corruption is rife.

A sense of despondency has set in that nothing can be done to stop it.

Not surprisingly, defectors nowadays describe an environment of social breakdown, petty crime, and a Darwinian struggle for survival. There is despondency and latent unrest.

And we support all of that with an intensive psychotherapy program to address the despondency, despair and depression that always accompanies severe, chronic pain.

The symptoms that Hippocrates associated with melancholic disorder aversion to food, despondency, sleeplessness, irritability, restlessness are remarkably similar to those contained in modern definitions of depressive disorder.

With fear gripping consumers, companies, and countries worldwide, talk has turned from a moderate advanced country recession to a major world depression. A sense of despondency has set in that nothing can be done to stop it.

Ms. Huff (Teach the Children International) said that over the past six years, she had watched as the men and women in the Saharan refugee camps had lost hope, leading to despondency and a breakdown in family structure.