It is caused by elevated levels of uric acid in the blood.

Treatment of uric acid gravel by phosphate of soda , Medical Gazette , p. 689, 23 August 1844.

In 1848, English physician Alfred Baring Garrod realized this excess uric acid in the blood was the cause of gout.

Gout occurs less than would be expected and lower levels of uric acid have been found in people with MS.

Other animals Gout is rare in most other animals due to their ability to produce uricase, which breaks down uric acid.

Urate lowering measures should be increased until serum uric acid levels are below 300 360 µmol l (5.0 6.0 mg dl), and are continued indefinitely.

And it came down to something called gout, which, as a result of kidney breakdown is actually uric acid crystals throughout the body, and worse in the joints, which made the gharial unable to swim.

And it came down to something called gout, which, as a result of kidney breakdown is actually uric acid crystals throughout the body, and worse in the joints, which made the gharial unable to swim.

They have found that the body s first line of defense against hemoglobin oxidation is a process of reduction, in which molecules like uric acid or ascorbic acid (vitamin C) impede oxidation by reducing the iron to a less oxidizing species.