Stage 4 Dissemination of tumor to distant lymph nodes, bone marrow, bone, liver, or other organs except as defined by Stage 4S.

Stage 4S Age 1 year old with localized primary tumor as defined in Stage 1 or 2, with dissemination limited to liver, skin, or bone marrow (less than 10 percent of nucleated bone marrow cells are tumors).

Rarely, the first sign of leukemia may be the development of a solid leukemic mass or tumor outside of the bone marrow, called a chloroma.

Benign tumor.

Yes, to the bone, to the very bone!

Tumor, was it?

The tumor in your leg is not consistent with a benign tumor.

My bone.

Your bone?

Dog, bone.

It's Bone.

One Bone.

And to think that the tumor was in the same bone, in the same place in my body as the accident 38 years earlier it seemed like too much of a coincidence.

And to think that the tumor was in the same bone, in the same place in my body as the accident 38 years earlier it seemed like too much of a coincidence.

So here's a tumor.

A brain tumor. Nice!

Radiation Radiotherapy is used when drug treatment is failing to control the pain of a growing tumor, such as in bone metastisis (most commonly), penetration of soft tissue, or compression of sensory nerves.

M Bone replies

That's David's bone.

Miss the bone?

Here's your bone.

seize a bone.

Artificial bone refers to bone like material created in a laboratory that can be used in bone grafts, to replace human bone that was lost due to severe fractures, disease, etc.

Is it a brain tumor?

This is called the hyoid bone. It's a bone which is right here.

I want you to meet Mr. Bone. How do you do, Mr. Bone?

The disease may affect just one bone, more than one bone at the same time, or more than one bone at different times.

Isn't it, Mr. Bone?

Ain't his name Bone?

Hello, Miss Le Bone.

In cancer research experiments, tumor cells are sometimes injected into an experimental animal to establish a tumor.

looking for small fragments of bone, fossil bone, that may be on the surface.

Elastin is the major component of ligaments (tissues that attach bone to bone) and skin.

So a bone cell reads only the set of instructions it needs to become bone.

And sure enough, Nanotyrannus has juvenile bone and the bigger one has more mature bone.

Chills me to the bone

It's produced in bone marrow.

Right to the funny bone.

It's just an old bone.

Goodbye, Major Applegate... Mr. Bone.

Mr. Bone. Isn't that amazing?

Like an old ham bone?

Dry as a bone outside.

I threw him a bone.

Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood.