Of the commonly produced compounds, ethylene dibromide is of greatest concern as it is both highly toxic and highly carcinogenic.

It is a petrochemical, manufactured from propylene and usually used close to the point of manufacture.

A representative of a Party operating under paragraph 1 of Article 5 observed that the destruction of CFCs contained in equipment and foams was becoming an increasingly urgent problem for many Parties operating under paragraph 1 of Article 5, as many refrigerators, for example, were nearing the end of their useful life.