Creatinine height ratio is calculated as 24 hour urine creatinine multiplied by 100 over the expected 24 hour urine creatinine for height.

The trend of serum creatinine levels over time is more important than absolute creatinine level.

Therefore, creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which correlates with the glomerular filtration rate (GFR).

(In the absence of secretion, creatinine behaves like inulin.

In both categories, the deterioration in kidney function is quantified either by an elevation in creatinine level in the blood, or by decreased clearance of creatinine in the urine.

Another diagnostic clue that helps differentiate CKD from ARF is a gradual rise in serum creatinine (over several months or years) as opposed to a sudden increase in the serum creatinine (several days to weeks).

While a baseline serum creatinine of 2.0 mg dl (150 μmol l) may indicate normal kidney function in a male body builder, a serum creatinine of 1.6 mg dl (110 μmol l) can indicate significant renal disease in an elderly female.

Using both ACEI and ARB concomitantly will increase creatinine levels to a greater degree than either of the two drugs would individually.

In a recent Japanese study, a lower serum creatinine level was found to be associated with an increased risk for the development of type 2 diabetes in Japanese men.

The typical human reference ranges for serum creatinine are 0.5 to 1.0 mg dl (about 45 90 μmol l) for women and 0.7 to 1.2 mg dl (60 110 μmol l) for men.

eGFR can be accurately calculated using serum creatinine concentration and some or all of the following variables sex, age, weight, and race, as suggested by the American Diabetes Association without a 24 hour urine collection.

In the absence of hematemesis, an upper source for GI bleeding is likely in the presence of at least two factors among black stool, age 50 years, and blood urea nitrogen creatinine ratio 30 or more.

Creatinine levels may be normal in the early stages of CKD, and the condition is discovered if urinalysis (testing of a urine sample) shows the kidney is allowing the loss of protein or red blood cells into the urine.

Patients are recommended for transplant if they have an arterial blood pH less than 7.3 after fluid resuscitation or if a patient has Grade III or IV encephalopathy, a prothrombin time greater than 100 seconds, and a serum creatinine greater than 300 mmol L In a 24 hour period.