Dave deBronkart Meet e Patient Dave

I had been blogging under the name Patient Dave, and when I discovered this, I just renamed myself e Patient Dave.

He said, Your shoulder's going to be fine, but Dave, there's something in your lung.

Most of her letters are to her husband, Alexander Duff Gordon and her mother, Mrs. Sarah Austin.

Their daughter, Janet Ann Ross (née Duff Gordon), was born in 1842 and died in 1927.

That's how it works. That's why we don't see the long lifespan, until we have the daf 2 mutant.

And mutations that damage the TOR gene just like the daf 2 mutations extend lifespan in worms and flies and mice.

Well when the daf 2 receptor is active, then it triggers a series of events that prevent FOXO from getting into the nucleus where the DNA is.

Well it turns out that in the daf 2 mutants, a whole lot of genes are switched on in the DNA that encode proteins that protect the cells and the tissues, and repair damage.

And what they found was that people who lived to 90 or 100 were more likely to have daf 2 mutations that is, changes in the gene that encodes the receptor for IGF 1.

And I went through a mental exercise actually, because I started a patient support community of my own on a website, and one of my friends, one of my relatives actually, said, Look, Dave, who grew this thing?

So after we made our discoveries with little C. elegans, people who worked on other kinds of animals started asking, if we made the same daf 2 mutation, the hormone receptor mutation, in other animals, will they live longer?